Abstract #3022

An Evaluation of Radial GRE Attenuation Correction Maps for Cardiac and Coronary PET-MRI Studies

Gillian Macnaught^1,2, Jack Andrews², David Brian¹, Kenneth Dolan¹, Philip M. Robson³, Zahi A. Fayad^3,4, Tim P Clark^1,5, Alison Fletcher^1,5, Matthias Fenchel⁶, Scott Semple^1,2, Edwin J.R. van Beek¹, David E. Newby^1,2, and Marc R. Dweck²

¹Edinburgh Imaging facility QMRI, The University of Edinburgh, Edinburgh, United Kingdom, ²The British Heart Foundation/University of Edinburgh Centre for Cardiovascular Sciences, The University of Edinburgh, Edinburgh, United Kingdom, ³Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ⁴Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ⁵Department of Nuclear Medicine, NHS Lothian, Edinburgh, United Kingdom, ⁶Siemens Healthcare GmbH, Erlangen, Germany

MR-based attenuation correction of PET images is essential for PET-MRI studies. An intensity threshold method for creating attenuation correction maps (µmaps) from 3D golden-angle radial spoiled gradient echo (radial GRE) images is presented. PET reconstructions using the Threshold µmaps, an existing radial GRE method for creating µmaps and the manufacturer Dixon VIBE µmaps are compared for quantification of ¹⁸F Sodium Fluoride (¹⁸F NaF) uptake in the aorta. Radial GRE µmaps better delineate the trachea and heart-lung boundaries. Dixon µmaps produced PET images with significantly lower aorta wall SUVmax values than radial GRE µmaps. µmaps must be characterised prior to implementation.

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