Meeting Banner
Abstract #3178

Improved susceptibility-weighted imaging of the thalamic nuclei at 7T with enhanced contrast and venous vessel exclusion

João Jorge1,2, Elena Najdenovska2,3, Constantin Tuleasca4,5,6, José P. Marques7, Marc Levivier4,6, Philippe Maeder3, Rolf Gruetter1,3,8, and Meritxell Bach Cuadra2,3,5

1Laboratory for Functional and Metabolic Imaging (LIFMET), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 2Medical Image Analysis Laboratory (MIAL), Center for Biomedical Imaging (CIBM), Lausanne, Switzerland, 3Department of Radiology, Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, 4Department of Clinical Neurosciences, Neurosurgery Service and Gamma Knife Center, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland, 5Signal Processing Laboratory, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland, 6Faculty of Biology and Medicine, University of Lausanne (UNIL), Lausanne, Switzerland, 7Donders Center for Cognitive Neuroimaging, Radboud University, Nijmegen, Netherlands, 8Department of Radiology, University of Geneva, Geneva, Switzerland

The thalamus plays a key role in neuronal signal transmission and modulation. While most of the current non-invasive imaging techniques fail to achieve substantial contrast between the thalamic nuclei, susceptibility-weighted imaging (SWI) has recently shown promising capabilities for their visualization at 7T, despite having been originally designed primarily for venous vessel imaging.

The aim of the present work was to optimize the SWI technique specifically for improved thalamic nuclei visualization, by jointly modifying the SWI combination and suppressing venous vessels. These modifications yielded substantially improved contrast and delineation of various thalamic nuclei, in good agreement with histological atlas information.

This abstract and the presentation materials are available to members only; a login is required.

Join Here