Meeting Banner
Abstract #3181

Multi-echo OxFlow for quantification of the cerebral metabolic rate of oxygen at 1.5T, 3T, and 7T

Erin K Englund1, Ana E Rodriguez-Soto1, and Felix W Wehrli1

1Radiology, University of Pennsylvania, Philadelphia, PA, United States

Fick’s principle can be used to quantify the cerebral metabolic rate of oxygen (CMRO2) as the product of oxygen extraction and blood flow. An interleaved dual-slice multi-echo GRE and phase contrast sequence, termed OxFlow, has previously been used for simultaneous measurement of SvO2 and blood flow. Here, we developed and evaluated an extended multi-echo OxFlow sequence designed for operation at multiple field strengths. The rate of phase accumulation, rather than the inter-echo phase difference, is used to compute SvO2. Results were obtained in 5 healthy subjects at 1.5T, 3T, and 7T, with agreement of the physiologic parameters between field strengths.

This abstract and the presentation materials are available to members only; a login is required.

Join Here