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Abstract #3183

A novel minimally invasive, image-guided neurablation technique using MRI - MINIMA

Christopher Payne1, John J Connell1, Matin J Mohseni1, Stephen Patrick1, Yichao Yu1, Bernard Siow1, Quentin A Pankhurst2, and Mark F Lythgoe1

1Centre for Advanced Biomedical Imaging, UCL, London, United Kingdom, 2Department of Medical Physics and Biomedical Engineering, UCL, London, United Kingdom

During tumour resection the goal is to remove a discrete region of cancerous tissue causing minimal damage to surrounding healthy tissue. Therefore, there is a demand for minimally invasive techniques, alongside MR imaging, for precise location of the tumour boundary. Presented here is the development of a minimally invasive, image-guided neurosurgery technique, whereby the position of an untethered surgical implant can be controlled and imaged in real time using an MRI scanner. We have demonstrated image-guided, precise movement of millimetre sized magnetic spheres inside ex vivo brain tissue by controlling the magnetic field gradients inside an MRI scanner.

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