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Abstract #3196

A pilot study of the effect of high pressure renal pelvic perfusion on the renal microstructure and microcirculation using multiparametric magnetic resonance imaging (mpMRI)

Qiong Ye1, Zhixian Yu1, Honghui Zhu1, Zhao Zhang1, and Jiance Li1

1The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China

Multiparametric MRI is widely used for tissue characterization. High pressure perfusion is commonly used in endoscopic surgery. In this study we compared the quantitative change of renal microstructure and microcirculation using DTI and simplified intravoxel incoherent motion imaging (sIVIM) in an operation simulating high pressure renal pelvic perfusion in the process of endoscopic surgery. Additionally, we compared the cortical and medullar difference. The results of this pilot study showed the feasibility of mpMRI to characterize renal physiology and investigate its quantitative change, with the potential value in early detection of renal function. But further study with larger sample size is required to draw a clear conclusion.

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