Meeting Banner
Abstract #3221

Critical Choices in ROI Analysis of Diffusion MRI Data

Mohammad Alipoor1 and Stephan E Maier1,2

1Radiology, University of Gothenburg, Gothenburg, Sweden, 2Radiology, Brigham and Women's Hospital, Boston, MA, United States

Diffusion parameters such as diffusivity, compartment fractions and diffusion signal itself are informative bio-markers in understanding and analyzing pathological changes in biological tissue. One frequently needs to compute a representative value of a diffusion parameter in a homogeneous ROI. Here we compare and contrast 3 common choices that researcher would make in the course ROI analysis. Though ROI analysis is deemed to be a common practice, the critical choices of computational methods (depending on noise distribution and underlying model) can considerably affect its findings and conclusions.

This abstract and the presentation materials are available to members only; a login is required.

Join Here