Whole-body medical imaging (such as MRI) can map many physical tissue parameters; however, there are currently many questions in the field regarding how changes in MRI are representative of changes in the underlying cells. To better understand these processes, we need to correlate MRI measurements with changes in microstructure. We created a living phantom for evaluation of techniques such as diffusion tensor imaging (DTI) that can be monitored and validated by optical techniques. Our future plan is to use MRI to study cell growth and monitor response to chemical and mechanical stimuli.
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