Abstract #3290

A novel method to detect fractional anisotropy differences in short association fibers discriminated by their functional connectivity between Multiple Sclerosis patients and healthy subjects

Cristian Montalba¹, Mariana Zurita^1,2, Tomas Labbe^1,3, Pamela Guevara⁴, Claudia Carcamo^3,5, Juan Pablo Cruz⁶, Carlos Sing-Long^1,7, Marcelo Andia^1,6, and Sergio Uribe^1,6

¹Biomedical Imaging Center, Pontificia Universidad Católica de Chile, Santiago, Chile, ²Electrical Engieneering, Pontificia Universidad Católica de Chile, Santiago, Chile, ³Interdisciplinary Center of Neurosciences, Pontificia Universidad Católica de Chile, Santiago, Chile, ⁴Faculty of Engineering, Universidad de Concepción, Chile, Concepción, Chile, ⁵Neurology Department, Pontificia Universidad Católica de Chile, Santiago, Chile, ⁶Radiology Department, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile, ⁷Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Católica de Chile, Santiago, Chile

We propose a novel method to evaluate fractional anisotropy (FA) differences in short association fibers (U-fibers) between patients with relapsing-remittent multiple sclerosis (RRMS) and healthy subjects by classifying each U-fiber in different groups according to their functional connectivity.

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