Abstract #3300

Cortical T2* and QSM maps at 7T: test-retest reproducibility, similarity and differences.

Tomohisa Okada¹, Koji Fujimoto¹, Yuta Urushibata², Hideto Kuribayashi², Tobias Kober^3,4,5, and Tadashi Isa¹

¹Human Brain Research Center, Kyoto University, Kyoto, Japan, ²Siemens Healthcare K.K., Tokyo, Japan, ³Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Swaziland, ⁴Department of Radiology, University Hospital (CHUV), Lausanne, Swaziland, ⁵LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

R2* and QSM measurement of the cortex is important to investigate human brain pathology. The 7T-MRI has a large potential to provide high-resolution information; however, measurement reliability has not been much investigated. This study investigated test-retest measurement reliability of cortical R2* and QSM values in 16 healthy subjects. High-resolution 3D multi-echo GRE imaging values were mapped onto the cortical surface extracted using 3D MP2RAGE images. Average maps show similar results for both R2* and QSM with larger variance at the frontotemporal base. Except these areas, measurement of cortical R2* and QSM values were found to be reliable at 7T.

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