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Abstract #3300

Cortical T2* and QSM maps at 7T: test-retest reproducibility, similarity and differences.

Tomohisa Okada1, Koji Fujimoto1, Yuta Urushibata2, Hideto Kuribayashi2, Tobias Kober3,4,5, and Tadashi Isa1

1Human Brain Research Center, Kyoto University, Kyoto, Japan, 2Siemens Healthcare K.K., Tokyo, Japan, 3Advanced Clinical Imaging Technology, Siemens Healthcare AG, Lausanne, Swaziland, 4Department of Radiology, University Hospital (CHUV), Lausanne, Swaziland, 5LTS5, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland

R2* and QSM measurement of the cortex is important to investigate human brain pathology. The 7T-MRI has a large potential to provide high-resolution information; however, measurement reliability has not been much investigated. This study investigated test-retest measurement reliability of cortical R2* and QSM values in 16 healthy subjects. High-resolution 3D multi-echo GRE imaging values were mapped onto the cortical surface extracted using 3D MP2RAGE images. Average maps show similar results for both R2* and QSM with larger variance at the frontotemporal base. Except these areas, measurement of cortical R2* and QSM values were found to be reliable at 7T.

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