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Abstract #3321

Whole heart First-pass spiral perfusion imaging with 1.25mm resolution at 3T

Yang Yang1, Christopher M Kramer1,2, and Michael Salerno1,2,3

1Medicine, University of Virginia, Charlottesville, VA, United States, 2Radiology, University of Virginia, Charlottesville, VA, United States, 3Biomedical Engineering, University of Virginia, Charlottesville, VA, United States

First-pass contrast-enhanced myocardial perfusion imaging is a useful noninvasive tool to evaluate patients with coronary artery disease, but current techniques are still limited in spatial-temporal resolution, and ventricular coverage which reduces the sensitivity to detect perfusion differences between the endocardium and epicardium and quantify ischemic burden. Outer-volume suppression (OVS) can achieve good signal suppression around the heart, but may have SAR limitations at 3T. In this study, we designed a spiral pulse sequence with slice-interleaved or simultaneous multi-slice (SMS) acquisition without OVS to achieve comparable high quality ultra-high 1.25mm resolution perfusion imaging. The sequences were tested in heathy volunteers and demonstrated high image quality.

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