Abstract #3322

Impact of native T1 on pixel-wise myocardial blood flow quantification

Corina Kräuter^1,2, Ursula Reiter¹, Clemens Reiter¹, Albrecht Schmidt³, Michael Fuchsjäger¹, Rudolf Stollberger², and Gert Reiter⁴

¹Department of Radiology, Medical University of Graz, Graz, Austria, ²Institute of Medical Engineering, Graz University of Technology, Graz, Austria, ³Department of Internal Medicine, Medical University of Graz, Graz, Austria, ⁴Research and Development, Siemens Healthineers, Graz, Austria

Native myocardial T1 varies between subjects and between segments, yet its impact on pixel-wise quantification of myocardial blood flow (MBF) has not been studied. 15 patients with coronary heart disease underwent 3T cardiac magnetic resonance native myocardial T1 mapping and perfusion imaging at rest. Nonlinearity correction for MBF calculation was performed employing literature native T1 values and patient-specific global as well as local native T1, respectively. Since reference T1 revealed substantial individual MBF errors and application of patient-specific global T1 overestimated MBF in perfusion deficit regions compared to local T1, patient-specific local native T1 should be employed for MBF quantification.

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