In hypertrophic cardiomyopathy (HCM), myocardium is disorganized, causing contraction abnormalities, perhaps before wall motion abnormalities are visually apparent. Tissue-tracking, a post-processing technique using routinely-acquired cine images, can assess strain, a multidimensional measure of contraction. We assess strain in 19 HCM cases. Global circumferential strain (GCS) and radial strain (GRS) correlated well (r > -0.85, p < 0.0001) and were worse in those with late gadolinium enhancement (p < 0.05). GCS modestly correlated with segment thickness (r = 0.46, p < 0.05). These data suggest strain may add value as a diagnostic/prognostic tool in assessment of HCM, available without additional imaging time.