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Abstract #3345

Monitoring intraluminal thrombus (ILT) progression in abdominal aortic aneurysm (AAA) using 3D black blood MRI: a longitudinal analysis

Chengcheng Zhu1, Lizhen Cao1,2, Zhaoying Wen1,3, David Saloner1, and Michael D Hope1

1Radiology, University of California, San Francisco, San Francisco, CA, United States, 2Radiology, Xuanwu Hospital, Beijing, China, 3Radiology, Anzhen Hospital, Beijing, China

The composition of intraluminal thrombus (ILT) is uniquely identified by MRI and has been suggested as a marker of abdominal aortic aneurysm (AAA) growth. However, the natural history of ILT progression is still unknown. This study followed 25 AAA patients over 19±9 months using repeated high resolution black-blood MRI. We found baseline ILT types did not predict AAA growth, however, AAAs with new ILT formation or fresher ILT during follow-up grew 3 times faster than AAAs without ILT change or older ILT (4.0±2.3mm/year vs. 1.3±2.5 mm/year, p=0.009). Monitoring ILT change provides new insights into the AAA risk assessment.

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