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Abstract #3433

Quantification of 3D aortic wall shear stress using k-t accelerated 4D flow MRI in under 2 minutes: a two center study

Emilie Bollache1, Kristopher Knott2, Redha Boubertakh2, Ryan Scott Dolan1, Claudia Camaioni2, Saadullah Ahmed-Villiers2, Thomas Treibel2, James C Carr1, Pim van Ooij3, Jeremy D Collins1, Julia Geiger4, James Moon2, Alex J Barker1, Steffen E Petersen2, and Michael Markl1,5

1Department of Radiology, Northwestern University, Chicago, IL, United States, 2Barts Heart Centre, London, United Kingdom, 3Department of Radiology, Academic Medical Center, Amsterdam, Netherlands, 4University Children's Hospital, Zurich, Switzerland, 5Department of Biomedical Engineering, Northwestern University, Chicago, IL, United States

Our aims were to study the feasibility at two centers of a newly developed k-t accelerated non-navigator gated 2-minute aortic 4D flow MRI sequence and to evaluate its wall shear stress (WSS) estimates. Eleven and 14 healthy volunteers, as well as 10 and 6 patients were scanned at Northwestern University and Barts Heart Centre, respectively. Despite an underestimation of distal aortic WSS in patients when compared to conventional 4D flow, our measurements were sensitive to expected aging and disease-related variations. We confirmed that aortic 4D flow MRI in 2 minutes is feasible and provides consistent WSS measurements.

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