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Abstract #3434

Quantitative evaluation of compressed sensing reconstruction in mouse phase contrast 4D-flow Magnetic Resonance Imaging

Moritz Braig1, Marius Menza1, Jochen Leupold1, Li Feng2, Pierre LeVan1, Juergen Hennig1, Axel J Krafft1, and Dominik von Elverfeldt1

1Radiology, Medical Physics, University Medical Center Freiburg, Freiburg, Germany, 2Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University School of Medicine, New York, NY, United States

Preclinical 4D-flow measurements remain challenging due to long acquisition times. This study presents a retrospective analysis of 4D-flow measurements with a radial 3D phase contrast sequence in combination with an advanced compressed sensing reconstruction. We evaluate the impact of different undersampling factors regarding peak velocities, flow, wall shear stress values and streamline analysis. We could show that high acceleration factors for preclinical phase contrast imaging can be used without substantially degrading the quantitative results. Our findings might enable high resolution 4D-flow acquisitions in less than one hour.

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