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Abstract #3554

Spiral-In/Out Multi Spin-Echo Acquisitions for Increased SNR in Dynamic Hyperpolarized 13C MRI

Shuyu Tang1, Robert Bok1, Eugene Milshteyn1, Daniel Vigneron1, and Peder Larson1

1University of California at San Francisco, San Francisco, CA, United States

The long T2 relaxation time of hyperpolarized 13C-labeled metabolites at 3T allows efficient use of hyperpolarized signal by multi spin-echo readouts. This work presents a novel 13C sequence that uses spiral in/out acquisitions at multiple spin echoes, each formed by a single adiabatic pulse to improve signal-to-noise ratio(SNR) in dynamic hyperpolarized 13C MRI. The proposed sequence was tested in vivo on a normal rat on a clinical 3T scanner. Results show that the proposed method has improved SNR for 15 dynamic acquisitions over 30s.

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