Meeting Banner
Abstract #3572

Hyperpolarization without a polarizer: in vivo 13C-MRI using SAMBADENA

Andreas B. Schmidt1,2, Stephan Berner1,3,4, Moritz Braig1, Mirko Zimmermann1, Jürgen Hennig1, Dominik von Elverfeldt1, and Jan-Bernd Hövener2,4

1Radiology - Medical Physics, University Medical Center Freiburg, Freiburg, Germany, 2Radiology and Neuroradiology, University Medical Center Schleswig-Holstein, Kiel, Germany, 3German Consortium for Cancer Research (DKTK), Heidelberg, Germany, 4German Cancer Research Center (DKFZ), Heidelberg, Germany

Hyperpolarization (HP) enhances the sensitivity of MR by several orders of magnitude and allows the detection of metabolism non-invasively and in vivo. However, well-established methods are costly, complex and require a dedicated “polarizer” next to the MRI system. SAMBADENA is, to date, the simplest and most cost-effective method to generate 13C-HP > 20 % for MRI. Within seconds HP is achieved within the MRI and little additional hardware is required. Here, the first in-vivo applications of SAMBADENA are reported, demonstrating its potential to be a fast, simple, low-cost alternative method for HP-MRI.

This abstract and the presentation materials are available to members only; a login is required.

Join Here