Chemical warfare nerve agents induce neurological damage through seizures. It is widely accepted in the field of nerve agent research that excitotoxicity is the main contributor to the neuropathology. Growing evidence suggests the involvement of hypoxia in seizure-related neuropathology. However, it is difficult to detect hypoxia without directly measuring oxygenation. We applied a method we developed to simultaneously quantify tissue oxygenation and cerebral blood flow to detect hypoxia following soman-induced seizures.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords