Meeting Banner
Abstract #3611

Structural and functional assessments of eye, brain and visual field in glaucoma using optical coherence tomography, magnetic resonance imaging and perimetry

Vivek Trivedi1, Yue Chen2, Carlos Parra1, Ahmel Arshad3, Ji Won Bang1, Mengfei Wu4, Ian Conner5, and Kevin Chan6

1Department of Ophthalmology, New York University, New York, NY, United States, 2Department of Biomedical Engineering, Tsinghua University, Beijing, China, 3Touro College of Osteopathic Medicine, Middletown, NY, United States, 4Department of Population Health, New York University, New York, NY, United States, 5Department of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, United States, 6Department of Ophthalmology, Department of Radiology, New York University, New York, NY, United States

We used 3-Tesla anatomical MRI, DTI, optical coherence tomography, and perimetry to assess structural and functional changes in the eye and brain in glaucoma patients across disease stages. Both optic nerve and optic chiasm volumes were found to decrease from early to advanced staged glaucoma, and were associated with inner retinal thinning and visual field functional loss. Fractional anisotropy, mean diffusivity, and radial diffusivity in optic radiation were significantly different from early to advanced staged patients, but not when comparing control to early disease states. These results suggest anatomical MRI and DTI may be useful in monitoring glaucomatous brain damages non-invasively across stages.

This abstract and the presentation materials are available to members only; a login is required.

Join Here