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Abstract #3670

Time makes the difference: Comparison of ADC values obtained with OGSE and PGSE sequences for differentiation of human head and neck tumors

Mami Iima1,2, Akira Yamamoto1, Ichiro Tateya3, Morimasa Kitamura3, Thorsten Feiweier4, Koichi Omori3, and Kaori Togashi1

1Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2Hakubi Center for Advanced Research, Kyoto University, Kyoto, Japan, 3Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 4Siemens Healthcare GmbH, Erlangen, Germany

The correlation of ADC values with different diffusion times, as obtained from OGSE and PGSE, was investigated in patients with head and neck tumors. A significant decrease of ADC values in head and neck cancers was noted with the increase of diffusion time (p < .0.05). Care needs to be taken when interpreting OGSE-ADC and PGSE-ADC values, as flow effects will contribute to these values, which was suspected in light of the (artefactual) increase of ADC values using PGSE compared to OGSE.

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