Abstract #3676

Including bone in DIXON-based PET/MRI attenuation correction for primary and recurrent prostate cancer

Mattijs Elschot¹, Kirsten M Selnæs^1,2, Håkon Johansen³, Brage Krüger-Stokke^1,3, Helena Bertilsson^4,5, and Tone F Bathen^1,2

¹Department of Circulation and Medical Imaging, NTNU, Norwegian University of Science and Technology, Trondheim, Norway, ²St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway, ³Department of Radiology and Nuclear Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway, ⁴Department of Urology, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway, ⁵Department of Cancer Research and Molecular Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway

Accurate correction for bone attenuation may be important for PET/MRI of prostate cancer due to the high bone-density of the pelvis. In this study we evaluated a previously proposed method that includes bone attenuation coefficients in the DIXON-based attenuation map by co-registration with an atlas of the major bones in the body. We found that the inclusion of bone significantly increased the standardized uptake values of soft tissue lesions, but the effect was only in the order of 3%. In addition, we observed that bone registration errors were present near 31% of the lesions, which may hamper widespread clinical applicability.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.