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Abstract #3686

Joint estimation applied to attenuation correction for quiescent period respiratory gated PET data in PET/MR

Sangtae Ahn1, Jaewon Yang2, Jing Liu2, Youngho Seo2, Thomas A. Hope2, Peder E. Z. Larson2, and Florian Wiesinger3

1GE Global Research, Niskayuna, NY, United States, 2Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States, 3GE Healthcare, Munich, Germany

Quiescent period gating of PET data reduces respiratory motion artifacts in PET imaging. However, a respiratory phase mismatch between attenuation map and gated PET data results in PET quantitation errors particularly for lesions in the dome of the liver. To address the problem, we apply a joint estimation (JE) technique to attenuation correction for respiratory phase gated PET data. We demonstrate on clinical PET/MR data that the JE method improves PET quantitation accuracy without an additional process of respiratory phase gating of MR data. JE has additional potential to estimate patient-specific lung tissue density and provide robustness to metallic implants.

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