Pulmonary fibrosis is typically an progressive, irreversible disease. However, in many cases, the onset of fibrosis is preceded by persistent inflammation; unfortunately, the two presentations are challenging to assess radiologically, and misdiagnoses can limit treatment options. In this in vivo rat study, the metabolic state the lung—derived via HP [1-13C]-pyruvate MRSI—and the structural heterogeneity of the lung—imaged via CT—were used in tandem to distinguish healthy lungs, inflamed lungs, and lungs with early onset fibrosis, creating an extremely sensitive tool for differentiating between the different phases of pulmonary fibrosis.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords