Meeting Banner
Abstract #3768

MR Spectroscopy Biomarker Discovery Algorithms (MBDA) to Discriminate PTSD from Blast Exposure and Healthy Controls

Nathan Tosh1,2, Laura Mariano3, Scott Quadrelli4, Graham Galloway1,2, Valerie Graves1, Aaron Urquhart1, Peter Malycha1,2, Katie Trickey1, Lisa Rich1, Rosanna Tremewan1, John Irvine3, and Carolyn Mountford1

1Translational Research Institute, Brisbane, Australia, 2Queensland University of Technology, Brisbane, Australia, 3Draper, Boston, MA, United States, 4University of Newcastle, Newcastle, Australia

Single Voxel Point RESolved Spectroscopy (PRESS) was used to obtain neuro-metabolite and lipid levels from the Posterior Cingulate Gyrus (PCG) of 4 cohorts – Control, Civilian PTSD, Artillery and Close Combat soldiers. Using a wavelet based statistical analysis approach classifiers were developed to objectively diagnose and monitor neuro-deregulation associated with PTSD and blast injury to artillery and to close combat soldiers.

This abstract and the presentation materials are available to members only; a login is required.

Join Here