Abstract #3786

Quantitative Dynamic Susceptibility Contrasted Perfusion in Differential Diagnosis of Recurrence and Radionecrosis for Brain Metastases after Stereotactic Radiotherapy

Bao Wang¹, Tianyi Qian², Bin Zhao³, Yingchao Liu⁴, and Na Sun¹

¹Shandong University, Jinan, China, ²MR Collaborations NE Asia, Siemens Healthcare, Beijing, China, ³Shandong Medical Imaging Research Institute, Jinan, China, ⁴Shandong Provincial Hospital, Jinan, China

Stereotactic radiotherapy (SRS) has become a widely used treatment for patients with brain metastases (BM). However, differential radionecorsis (RN) and tumor recurrence (TR) after SRS for BM by MR images is still challenging. In this study, a quantitative dynamic susceptibility contrasted perfusion weighted imaging (DSC-PWI) technique was applied to solve this problem. The results showed that quantitative DSC-PWI had higher diagnostic efficiency and smaller inter-observer differences than traditional DSC-PWI.

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