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Abstract #3786

Quantitative Dynamic Susceptibility Contrasted Perfusion in Differential Diagnosis of Recurrence and Radionecrosis for Brain Metastases after Stereotactic Radiotherapy

Bao Wang1, Tianyi Qian2, Bin Zhao3, Yingchao Liu4, and Na Sun1

1Shandong University, Jinan, China, 2MR Collaborations NE Asia, Siemens Healthcare, Beijing, China, 3Shandong Medical Imaging Research Institute, Jinan, China, 4Shandong Provincial Hospital, Jinan, China

Stereotactic radiotherapy (SRS) has become a widely used treatment for patients with brain metastases (BM). However, differential radionecorsis (RN) and tumor recurrence (TR) after SRS for BM by MR images is still challenging. In this study, a quantitative dynamic susceptibility contrasted perfusion weighted imaging (DSC-PWI) technique was applied to solve this problem. The results showed that quantitative DSC-PWI had higher diagnostic efficiency and smaller inter-observer differences than traditional DSC-PWI.

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