Abstract #3789

Motion of the cerebellum in patients with Chiari malformation compared to healthy subjects: A quantitative study using spiral cine DENSE MRI

John Oshinski¹, Soroush Heidari Pahlavian², Jordan Schuster ¹, Xiaodong Zhong^1,3, Rouzbeh Amini², Francis Loth², and Daniel Barrow¹

¹Radiology and Imaging Sciences, Emory University, Atlanta, GA, United States, ²Mechanical Engineering, University of Akron, Akron, OH, United States, ³Research and Development, Siemens Healthineers, Atlanta, GA, United States

The goal of this study was to acquire mid-sagittal cine DENSE images to quantify displacement and strain over the cardiac cycle in patients with Chiari malformation and age-matched controls. The major finding of this study was that both tissue displacement and tissue strain in the parenchyma of the cerebellum was significantly greater in patients with Chiari malformation than healthy controls.

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