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Abstract #3806

Use of a Rigidity Penalty to Improve MR-CT Image Registration

Elizabeth MaryAnn McKenzie1, Dan Ruan2, Percy Lee2, and Ke Sheng2

1Physics and Biology in Medicine, University of California Los Angeles, LOS ANGELES, CA, United States, 2Radiation Oncology, University of California Los Angeles, Los Angeles, CA, United States

Attenuation coefficients of tissue must be known to accurately model dose in radiation therapy. MR-guided radiation therapy better visualizes soft tissue, but it does not inherently contain attenuation information in the same way as CT images. CT and MR images can be registered to pool information, but the bones can become severely distorted. This work applies a rigidity penalty to bones segmented in CT, such that the soft tissue is allowed to deform while the bones remain rigid during CT to MRI registration. We show that this technique improves the registration, making the deformations more anatomically feasible.

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