Abstract #3807

4D-MRI in radiotherapy: motion phantom study and automatic sorting based on internal surrogate for motion management during free breathing

Soleakhena Ken¹, Oliver Bieri², Zarko Celicanin², Philippe Cattin³, and Laure Parent¹

¹Department of Engineering and Medical Physics, Institut Universitaire du Cancer de Toulouse - Oncopole, Toulouse, France, ²Department of Medical Physics, University of Basel, Basel, Switzerland, ³Department of Biomedical Engineering, University of Basel, Basel, Switzerland

4D-MRI sequence for radiotherapy (RT) application is validated in this study on a motion phantom and on healthy volunteers. 4D-MR imaging of a moving spherical target with different signal waveforms gave similar results as for classical 4D-CT used in RT planning. During free breathing 4D-MRI acquisitions, the internal surrogates, defined as the mean intensity inside a region of interest are relevant to detect the different respiratory phases for consistent retrospective automatic image sorting. Feasibility of integration into treatment planning system was also demonstrated, allowing picturing the dynamic behavior of the moving organ for treatment planning.

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