Abstract #3808

Comparative evaluation of DTI and FLAIR images in assessment of whole pathological region in GBM patients for RT planning; a semi-automatic segmentation approach

Manijeh Beigi¹, Mojtaba Safari¹, Ahmad Ameri², Mohsen ShojaeeMoghadam³, and Hamidreza SalighehRad¹

¹Quantitative MR Imaging and Spectroscopy Group, Research Center for Cellular and Molecular Imaging, Institute for Advanced Medical Imaging, Tehran University of Medical Sciences, Tehran, Iran (Islamic Republic of), ²Clinical Oncology, Shahid Beheshti University of Medical Science, Tehran, Iran (Islamic Republic of), ³Payambaran Imaging Center, Tehran, Iran (Islamic Republic of)

Accurate determination of whole pathological region is still a challenging task and necessary prerequisite step in radiotherapy planning in GBM. This study attempted to propose semi-automatic segmentation method that can extract whole pathogenic tumor on T₂-FLAIR and isotropic component (p-map) of diffusion tensor imaging(DTI) with over 90 % sensitivity, specificity and dice score. In addition, the extension of pathological region was compared. Results show that there is significant difference between segmented region on T₂-FLAIR and p map. Beyond usual segmentation method for T₂-FLAIR, we have highlighted DTI parametric maps because of its information on tumor infiltration.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.