In this study, we aimed to assess the potential of using intravoxel incoherent motion (IVIM) for measuring cerebral blood volume (CBV) in brain metastases and normal brain tissue. DWI was acquired with b=0, 200, 300 and 1000s/mm2 in nineteen patients with 23 brain metastases from lung cancer. Asymptotic IVIM fitting yielded an estimation of the perfusion fraction, and subsequent estimation of CBV. CBVDWI in brain metastases and gray matter correlated significantly with CBV obtained from conventional DSC MRI. Our results suggest that IVIM may serve as an independent and reliable surrogate marker of blood volume in well perfused brain tissue.