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Abstract #3826

Standard Diffusion-Weighted, Diffusion Kurtosis and Intravoxel Incoherent Motion MR Imaging of Sinonasal Malignancies: Correlations with Ki-67 Proliferation Status

Zebin Xiao1, Zuohua Tang1, Jinwei Qiang2, Yufeng Zhong2, Rong Wang1, and Zhongshuai Zhang3

1Radiology, Eye & ENT Hospital of Fudan University, Shanghai, China, 2Jinshan Hospital of Fudan University, Shanghai, China, 3Siemens Healthcare Ltd., Shanghai, China

This study aimed to explore the correlations between parameters derived from standard diffusion-weighted imaging (DWI), diffusion kurtosis imaging (DKI) and intravoxel incoherent motion (IVIM) with the Ki-67 proliferation status. Our preliminary study shows that DWI-derived parameters from different models are capable of providing different pathophysiological information. DWI, DKI and IVIM parameters are associated with Ki-67 proliferation status. Kmax derived from DKI is the strongest independent factor for the prediction of Ki-67 proliferation status.

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