Abstract #3826

Standard Diffusion-Weighted, Diffusion Kurtosis and Intravoxel Incoherent Motion MR Imaging of Sinonasal Malignancies: Correlations with Ki-67 Proliferation Status

Zebin Xiao¹, Zuohua Tang¹, Jinwei Qiang², Yufeng Zhong², Rong Wang¹, and Zhongshuai Zhang³

¹Radiology, Eye & ENT Hospital of Fudan University, Shanghai, China, ²Jinshan Hospital of Fudan University, Shanghai, China, ³Siemens Healthcare Ltd., Shanghai, China

This study aimed to explore the correlations between parameters derived from standard diffusion-weighted imaging (DWI), diffusion kurtosis imaging (DKI) and intravoxel incoherent motion (IVIM) with the Ki-67 proliferation status. Our preliminary study shows that DWI-derived parameters from different models are capable of providing different pathophysiological information. DWI, DKI and IVIM parameters are associated with Ki-67 proliferation status. Kmax derived from DKI is the strongest independent factor for the prediction of Ki-67 proliferation status.

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