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Abstract #3835

Towards an ultra-high field virtual biopsy for hepatic cancers using phospholipid metabolism

Deb Rivera1,2,3, IML van Kalleveen3, Catalina Arteaga de Castro4, Hanneke Laarhoven3, Dennis Klomp1,4, Wybe van der Kemp4, Jaap Stoker3, and Aart Nederveen3

1MR Coils BV, Zaltbommel, Netherlands, 2Spinoza Centre, Amsterdam, Netherlands, 3Academic Medical Center, Amsterdam (AMC), Amsterdam, Netherlands, 4University Medical Center Utrecht (UMCU), Utrecht, Netherlands

At 7T 31P spectroscopy becomes possible on clinically relevant scales. Here we tackle the greatest challenge in multi-parametric imaging at high-field – creating localizers and radiological-grade images in the body in the absence of a bore body coil. By using antennas rather than loop coils, we image the full extent of the liver (n=10). Combining antennas with parallel transmit, allows radiological-grade images. Although technically feasible, it is not yet possible to obtain multi-nuclear spectra and parallel transmit images within the same scan session. We combine the methods by rebooting the scanner mid-exam, and demonstrate the method can be used for imaging patients.

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