Abstract #3846

High Resolution Semi-LASER Localized Echo Planar Spectroscopic Imaging at Ultra High Field

Eduardo Coello^1,2, Ralph Noeske³, Brian L. Burns⁴, Jeremy W. Gordon⁵, Angela Jakary⁵, Bjoern Menze¹, Axel Haase¹, Peder E.Z. Larson⁵, Yan Li⁵, and Rolf F. Schulte²

¹Technische Universität München, Munich, Germany, ²GE Healthcare, Munich, Germany, ³MR Applied Science Lab Europe, GE Healthcare, Berlin, Germany, ⁴MR Applied Science Lab, GE Healthcare, Menlo Park, CA, United States, ⁵Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States

This work presents a robust framework for fast high-resolution ¹H MRSI at 7 Tesla using semi-localized by adiabatic selective refocusing (semi-LASER) and high-bandwidth symmetric echo planar spectroscopic imaging (EPSI). Inconsistencies in the symmetric EPSI trajectory are corrected using a single shot water reference scan, effectively removing spectral ghosting. With the proposed methodology, high-resolution metabolite ratio maps that show correlation with anatomical structures were obtained under 5-minutes.

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