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Abstract #3847

Whole Brain 5mm-isotropic 3D 1H-FID-MRSI accelerated with Compressed-Sensing SENSE

Antoine Klauser1, Sebastien Courvoisier1, Michel Kocher1, Dimitri Van De Ville1,2, and Francois Lazeyras1

1Radiology and Medical Informatics, University of Geneva, Geneva, Switzerland, 2Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

Proton FID-MRSI sequence was implemented in 3D to measure metabolite distributions over whole brain up to 5mm-isotropic resolution. MRSI dataset was reconstructed through a Low-Rank-TGV model enabling Compressed-sensing SENSE acceleration. Acceleration performance was assessed quantitatively on a-posteriori 6.6mm-isotropic dataset showing good agreement up to a factor 2. As proof of concept, metabolite images of a 5mm-isotropic dataset accelerated by a factor 2 were acquired and reconstructed.

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