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Abstract #3848

Effect of the phase variation induced by eddy currents on localized spectroscopy fatty acid composition quantification and its correction

Angéline Nemeth1, Benjamin Leporq1, Amandine Coum2,3, Giulio Gambarota2,3, Kévin Seyssel4, Bérénice Segrestin5, Pierre-Jean Valette6, Martine Laville5, Olivier Beuf1, and Hélène Ratiney1

1Univ. Lyon, INSA‐Lyon, Université Claude Bernard Lyon 1, UJM-Saint Etienne, CNRS, Inserm, CREATIS UMR 5220, U1206, F69621, VILLEURBANNE, France, Lyon, France, 2INSERM, UMR 1099, Rennes, France, Rennes, France, 3Univ Rennes 1, LTSI, Rennes, France, Rennes, France, 4Department of Physiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Lausanne, Switzerland, 5Centre de Recherche en Nutrition Humaine Rhône-Alpes (CRNH-RA), Centre Hospitalier Lyon Sud, Pierre-Bénite, Lyon, France, 6Hospices Civils de Lyon, Département d'imagerie digestive, CHU Edouard Herriot, Lyon, Lyon, France

Monte Carlo simulations and in vivo measurements on human abdominal adipose tissue were used to analyze the effect of the phase variation induced by eddy currents on localized spectroscopy fatty acid composition quantification (proportion of polyunsaturated, monounsaturated and saturated fatty acid). Monte Carlo simulations showed that base line distortions were able to strongly impact estimation of fatty acid composition. So we proposed a simple method to correct the base line using a second signal acquired with a longer TE. Test-retest variability of quantitative results was reduced using this correction.

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