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Abstract #3853

Spatially localized pure shift 1H MRS for biological tissues at 7 T

Yuqing Huang1, Weinan Lai1, and Zhong Chen1

1Department of Electronic Science, Xiamen University, Xiamen, China

Proton magnetic resonance spectroscopy (1H MRS) presents an effective tool for in vivo studies on biological tissues by the non-invasive detection manner. However, due to limited proton chemical shift range and extensive J coupling splittings, spectral congestions or even overlapping are generally encountered in resulting 1D 1H MRS acquired by routine STimulated Echo Acquisition Mode (STEAM) and Point resolved spectroscopy (PRESS) experiments. In this report, we presents a previously-unreported MAS approach to obtain spatially localized 1D pure shift spectra with spectral simplification, potentially useful for studies on biological samples.

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