Proton magnetic resonance spectroscopy
(1H MRS) presents an effective tool for in vivo studies on biological tissues by the non-invasive detection manner. However, due to limited proton
chemical shift range and extensive J coupling splittings,
spectral congestions or even overlapping are generally encountered in resulting
1D 1H MRS acquired by routine STimulated Echo
Acquisition Mode (STEAM) and Point resolved spectroscopy (PRESS) experiments. In this report, we presents a previously-unreported
MAS approach to obtain spatially localized
1D pure shift spectra with spectral simplification, potentially useful for studies on biological
samples.
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