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Abstract #3872

Improved Encoding Efficiency in Sodium MRI with Zero-Gradient-Excitation Ramped Hybrid Encoding (zGRF-RHE)

Yasmin Blunck1,2, Bradford A Moffat2, Scott C Kolbe2, Roger J Ordidge2, Jon O Cleary2, and Leigh A Johnston1,2

1Biomedical Engineering, University of Melbourne, Melbourne, Australia, 2Melbourne Brain Centre Imaging Unit, University of Melbourne, Melbourne, Australia

The fast signal decay in sodium MRI makes high quality image acquisition challenging. Here we enhance image quality by improving encoding time (tenc) efficiency using a special case of ramped hybrid encoding , zero-gradient-under-RF-excitation RHE (zGRF-RHE). This provides 1) gradient-free-excitation for high flip angle, non-selective excitation profiles necessitated by low signal in sodium MRI and 2) gradient ramping during deadtime for optimised tenc, to reduce T2 decay influence during acquisition. The performance of zGRF-RHE is demonstrated in simulations, phantom and in vivo experiments and improves image quality (SNR and T2 blurring). It is applicable to any centre-out trajectory design.

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