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Abstract #3909

Correlations Between Brain Structural Volumes and Brain Metabolite Concentrations in Alzheimer’s Disease: Preliminary Results from the NeuroMet Project

Ariane Fillmer1, Theresa Köbe2, Semiha Aydin1, Laura Goeschel2, Agnes Flöel2,3, Florian Schubert1, and Bernd Ittermann1

1Physikalisch-Technische Bundesanstalt (PTB), Berlin, Germany, 2Department of Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany, 3Department of Neurology, University Medicine Greifswald, Greifswald, Germany

The NeuroMet project aims to identify new biomarkers for Alzheimer’s disease (AD) and to reduce measurement uncertainties for known biomarkers for AD. This work presents first NeuroMet results with a focus on ultra-high field MR imaging and MR spectroscopy. Significant correlations were found between volumes of cortical and subcortical gray matter structures and concentrations of NAA, glutamate and GABA.

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