Abstract #3918

Hydrogen magnetic resonance spectroscopy: a technique for predicting clinical outcome in patients with head & neck squamous cell cancer with locally advanced cervical nodal disease

Sola Adeleke¹, Marianthi-Vasiliki Papoutsaki², Harbir Sidhu², Alan Bainbridge³, David Price³, Dawn Carnell⁴, Martin Forster⁵, Ruheena Mendes⁴, and Shonit Punwani¹

¹Centre for medical imaging, University College London(UCL), London, United Kingdom, ²Centre for medical imaging, University College London, London, United Kingdom, ³Dept of medical physics and biomechanical engineering, University college london hospitals, London, United Kingdom, ⁴Dept of oncology, University college london hospitals, London, United Kingdom, ⁵Research department of oncology, University college london, London, United Kingdom

Hydrogen magnetic resonance spectroscopy (1H-MRS) is a technically challenging modality. It has the potential to provide specific metabolic information that could guide clinical decision making. In this study we assess feasibility of performing 1H MRS in patients with head and neck squamous cell carcinoma (HNSCC) prior to treatment and explore its correlation with post-treatment outcomes.

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