Abstract #3966

Non-water Suppressed GABA Edited Magnetic Resonance Spectroscopic Imaging using Density Weighted Concentric Rings k-space Trajectory

Uzay E Emir¹, Pingyu Xia¹, Xiaopeng Zhou¹, Mark Chiew², Adam Steel^3,4, M Albert Thomas⁵, and Ulrike Dydak^1,6

¹School of Health Sciences, Purdue University, West Lafayette, IN, United States, ²Wellcome Centre for Integrative Neuroimaging, FMRIB Division, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, ³Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, ⁴National Institute of Mental Health, National Institutes of Health, Bethesda, MD, United States, ⁵Department of Radiological Sciences, University of California, Los Angeles, CA, United States, ⁶Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States

In this study, we have developed and demonstrated a non-water suppressed GABA editing Magnetic Resonance Spectroscopic Imaging technique using density-weighted concentric rings k-space trajectory that performs robustly within a clinically feasible acquisition time at 3T. The method has been validated in a series of phantom experiments and its feasibility assessed in a healthy volunteer with a high in-plane resolution of 7.5 × 7.5 mm². Experiments qualitatively demonstrate the advantage of the proposed method in terms of its improved resolution and reduced contamination of spectra from neighboring voxels.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.