Abstract #3988

31P MRS of the frontal lobe of human brain at 7T

Shizhe Steve Li¹, Li An¹, Jan Willem van der Veen¹, Maria Ferraris Araneta¹, Johnson Christopher¹, Yu Shao², Shumin Wang¹, Jun Shen¹, and Jun Shen¹

¹National Institutes of Health, Bethesda, MD, United States, ²Chongqing University of Posts and Telecommunications, Chongqing, China

The majority of neuropsychiatric disorders are thought to be originated in the frontal lobe. Increasing the SNR of frontal lobe ³¹P MRS using a surface coil can be very important because many MRS manifestations of psychiatric illnesses could be subtle. This study demonstrates the feasibility of high SNR ³¹P MRS of human frontal lobe using a surface coil and 3D CSI at 7 Tesla. Comparing to the occipital lobe spectra acquired from the same subject it was shown that the sensitivity and spectral resolution of ³¹P MRS spectra of the frontal lobe can be made comparable to that of the occipital lobe.

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