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Abstract #3989

Influence of BMI and hepatic lipids on absolute quantification of 31P metabolites at 7T

Lorenz Pfleger1,2, Martin Gajdošík1,3, Peter Wolf1, Sabina Smajiš1, Paul Fellinger1, Sigfried Trattnig2,4, Michael Krebs1, Marek Chmelík2,5,6, and Martin Krššák1,2

1Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria, 2High-field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 3Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, 4Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, 5Faculty of Healthcare, University of Prešov, Prešov, Slovakia, 6Department of Radiology, General Hospital of Levoča, Levoča, Slovakia

This study focuses on absolute quantification of hepatic 31P metabolites at ultra-high field (7T) and the possible influence of BMI and hepatocellular content of lipids (HCL) on the calculated metabolite concentrations. Significant differences were found in γ- and α-ATP as well as in Pi content for population groups with normal and high BMI. With the assessment of HCL it is possible to correct for those differences and no significances could be reported after.

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