Abstract #3989

Influence of BMI and hepatic lipids on absolute quantification of 31P metabolites at 7T

Lorenz Pfleger^1,2, Martin Gajdošík^1,3, Peter Wolf¹, Sabina Smajiš¹, Paul Fellinger¹, Sigfried Trattnig^2,4, Michael Krebs¹, Marek Chmelík^2,5,6, and Martin Krššák^1,2

¹Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria, ²High-field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ³Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, ⁴Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, ⁵Faculty of Healthcare, University of Prešov, Prešov, Slovakia, ⁶Department of Radiology, General Hospital of Levoča, Levoča, Slovakia

This study focuses on absolute quantification of hepatic ³¹P metabolites at ultra-high field (7T) and the possible influence of BMI and hepatocellular content of lipids (HCL) on the calculated metabolite concentrations. Significant differences were found in γ- and α-ATP as well as in P_i content for population groups with normal and high BMI. With the assessment of HCL it is possible to correct for those differences and no significances could be reported after.

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