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Abstract #4046

Experimental demonstration of a HIFU self-scanning treatment in moving tissue using hybrid ultrasound and MR guidance

Orane Lorton1, Laura Gui-Lévy1, Pauline Guillemin1, Nadia Möri2, Philippe Cattin2, Sylvain Terraz3, Christoph Becker3, and Rares Salomir3

1Radiology, University of Geneva, Faculty of medicine, Geneva, Switzerland, 2Biomedical Engineering, Center of Medical Image Analysis and Navigation, University of Basel, Basel, Switzerland, 3Radiology, Geneva Hospitals, Geneva, Switzerland

MRI-controlled tumor treatment by High Intensity Focused Ultrasound (HIFU) is challenging in the abdominal organs because of the breathing motion. We experimentally demonstrated a self-scanning method for motion compensation by passively scanning the tissue passing through the static focal point. Ex vivo turkey samples were subjected to a breathing-like non-periodic motion and the HIFU power was modulated using the velocity information from landmark tracking on simultaneous ultrasound images. MR imaging provided targeting and on-line thermometry. Temperature map were computed using the reference-less PRFS method. A dramatic improvement of the isotherms uniformity score was achieved for rectilinear volumetric ablation.

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