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Abstract #4049

Shear stiffness determination using MR-acoustic radiation force imaging

Bradley D. Bolster, Jr.1, Henrik Odéen2, Hailey McLean2, Dennis L. Parker2, and Allison Payne2

1Siemens Medical Solutions USA, Inc., Salt Lake City, UT, United States, 2Radiology and Imaging Sciences, University of Utah, Salt Lake City, UT, United States

Magnetic resonance acoustic radiation force imaging (MR-ARFI) has been used pre-clinically to detect tissue displacement changes during magnetic resonance guided focused ultrasound treatments. Although displacement is a quantitative metric, shear stiffness is typically used to clinically describe disease states. This work develops and evaluates a model-based technique to determine tissue shear stiffness from MR-ARFI displacement measurements. The MR-ARFI derived values are compared to conventional MR elastography shear stiffness values in a phantom study.

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