Abstract #4057

Assessment of Iron Oxide Nanoparticle Concentration for Distinct Intercranial EEG Electrode Localization in MRI

Johannes B. Erhardt^1,2, Jessica A. Martinez², Tyler E Cork², Isabel Gessner³, Sanjay Mathur³, Thomas Stieglitz¹, and Daniel B. Ennis²

¹University of Freiburg, Freiburg, Germany, ²UCLA, Los Angeles, CA, United States, ³University of Cologne, Cologne, Germany

IcEEG electrodes for epilepsy and research applications impair fMRI and MR images with compromising susceptibility artifacts. Thin-film implants feature 100x less metal thickness and thus minimal artifacts. However, thin-film implants are inconspicuous in MRI. Therefore we present means of localization using super paramagnetic iron oxide nano particles to make thin-film implants ready for future applications. We present feasible concentrations and proof of concept.

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