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Abstract #4121

Nyquist Artifact Correction for Multi-band and Multi-shot EPI Using Multiplexed Sensitivity Encoding (MUSE) - A Self-reference 2D Phase Correction Method

Xiaoxi Liu1, Di Cui1, Edward S. Hui1,2, Queenie Chan3, Nan-Kuei Chen4,5, and Hing-Chiu Chang1

1Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, Hong Kong, 2The State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong, Hong Kong, 3Philips Healthcare, Hong Kong, Hong Kong, 4Department of Biomedical Engineering, University of Arizona, Tucson, AZ, United States, 5Brain Imaging and Analysis Center, Duke University Medical Center, Durham, NC, United States

Echo planar imaging (EPI) suffers from Nyquist artifact that is typically corrected by using 1D phase correction with reference scan. In oblique-plane acquisition, 2D phase corrected is warranted to effectively reduce Nyquist artifact. However, Nyquist artifact correction is challenging in the case of multi-band EPI due to the presence of slice-dependent phase error. In this study, we aim to develop a self-reference 2D phase correction method to eliminate the Nyquist artifact in multi-band multi-shot EPI data, which utilizes the recently developed multiplexed sensitivity encoding (MUSE) reconstruction algorithm.

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