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Abstract #4122

Removal of Pseudo-lesion Artifact in Diffusion-Weighted Echo-Planar Imaging Using Virtual Coil Acquisition and Multiplexed Sensitivity Encoding (MUSE)

Xiaoxi Liu1, Edward S. Hui1,2, and Hing-Chiu Chang1

1Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, Hong Kong, 2The State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Hong Kong, Hong Kong

In routine brain DW-EPI with SENSE, the pseudo-lesion artifact due to residual aliasing of eyeball has been previously reported. We have found that the incidence of pseudo-lesion artifact was over 50% when performing double-oblique imaging on stroke patients. The possible cause is highly likely related to inference between residual Nyquist ghost and unfolding process in SENSE reconstruction. In this study, we propose a self-reference method to effectively remove pseudo-lesion artifact in double-oblique DW-EPI using virtual coil acquisition and multiplexed sensitivity encoding (MUSE). Our proposed method reveals higher image quality, better SNR performance, and lower artifact level than conventional SENSE reconstruction.

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