Abstract #4173

Validation study of high framerate source localization for MR-guided HDR brachytherapy

Ellis Beld¹, Marinus A. Moerland¹, Max A. Viergever², Jan J.W. Lagendijk¹, and Peter R. Seevinck²

¹Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands, ²Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands

For the development of MR-guided high-dose-rate (HDR) brachytherapy, the accuracy and precision of an MR-based HDR source localization method were investigated in a phantom study, by a comparison with CT. MR images were acquired for various angulations of the source with respect to B₀, and a 3D CT scan was acquired. The MR source positions were compared to the CT source position. The results demonstrated a high, subvoxel accuracy (0.4-0.6 mm) and a high precision (≤0.1 mm) at high temporal resolutions (0.15-1.2 s per slice). This proved that our proposed MR-based source localization method is valuable for MR-guided HDR brachytherapy.

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