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Abstract #4173

Validation study of high framerate source localization for MR-guided HDR brachytherapy

Ellis Beld1, Marinus A. Moerland1, Max A. Viergever2, Jan J.W. Lagendijk1, and Peter R. Seevinck2

1Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands, 2Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands

For the development of MR-guided high-dose-rate (HDR) brachytherapy, the accuracy and precision of an MR-based HDR source localization method were investigated in a phantom study, by a comparison with CT. MR images were acquired for various angulations of the source with respect to B0, and a 3D CT scan was acquired. The MR source positions were compared to the CT source position. The results demonstrated a high, subvoxel accuracy (0.4-0.6 mm) and a high precision (≤0.1 mm) at high temporal resolutions (0.15-1.2 s per slice). This proved that our proposed MR-based source localization method is valuable for MR-guided HDR brachytherapy.

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