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Abstract #4195

Linear contrast agent-induced high signal intensity in the dentate nucleus and globus pallidus on unenhanced T1-weighted images in pediatric patients

Shintaro Ichikawa1, Utaroh Motosugi1, Yoshie Omiya1, and Hiroshi Onishi1

1Department of Radiology, University of Yamanashi, Chuo-shi, Japan

Hyperintensity in the dentate nucleus (DN) and globus pallidus (GP) on unenhanced T1-weighted images (T1WI) was associated with previous administration of linear gadolinium-based contrast agent (GBCA) in pediatric patients. The DN-to-pons ratio increased as the number of linear GBCAs administrations increased. The GP-to-thalamus ratio of the “Linear GBCAs ≥ 5 administrations” group was significantly higher than that of the “No GBCAs administration” and the “Linear GBCAs 1–4 administrations” groups. The number of previous administrations of linear GBCAs was positively correlated with the DN-to-pons ratio and the GP-to-thalamus ratio.

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