Abstract #4268

High-dimensional and accurate dictionary fitting with B-spline interpolation and gradient-based optimization

Willem van Valenberg^1,2, Stefan Klein², Frans M. Vos^1,3, Lucas J. van Vliet¹, and Dirk H.J. Poot^1,2

¹Quantitative Imaging Group, Delft University of Technology, Delft, Netherlands, ²Biomedical Imaging Group, Erasmus Medical Center, Rotterdam, Netherlands, ³Department of Radiology, Academic Medical Center, Amsterdam, Netherlands

Dictionary matching in MR fingerprinting acquisitions quantifying many parameters, such as T₁ T₂, T₂’, B₀, B₁⁺, and PD, becomes prohibitively expensive due to the dense grid in each dimension of the dictionary that is required. In this work we propose B-spline interpolation of the dictionary to reduce the dictionary size and to enable efficient nonlinear least-squares fitting by gradient-based optimization methods. The experiments show that the method substantially reduces fitting error, especially when the SNR is high and dictionary resolution is the limiting factor for improving the precision of the quantitative parameters.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.